350 kilometers per hour! China’s high-speed rail conducts "up-to-speed" test

　　What signals did Taobao release in the "first case" of winning the fake sale?

　　International long-distance phone tariffs will continue to decrease

　　Our country set up an "aircraft carrier" for clinical research on major diseases

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　　What were the major events of the past week? Which ones are worth paying attention to? Which ones are relevant to you? Please see the review of the major events of the week.

　　[Fuxing] 350 kilometers per hour! The reporter takes you to experience the "up-speed" test of China’s high-speed rail

　　At 8:38 on the 27th, the "Fuxing", a standard Chinese EMU, pulled out of the Beijing South Railway Station and accelerated in an instant. After more than four hours, it made a round-trip between Beijing and Xuzhou on the Beijing-Shanghai high-speed rail. Along the way, the "Fuxing" has a top speed of 352 kilometers per hour. Six years later, China’s high-speed rail has ushered in this "up-to-speed" test, heralding the return of China’s 350-kilometer high-speed rail era.

　　[straight-A student choir] Tsinghua super "straight-A student choir" sings and cries countless netizens, with an average age of over 72 years old

　　"I love you, China. I love you, China, and I want to dedicate my beautiful youth to you…" A group of elderly people with an average age of 72.3 years, with tears in their eyes, sang the popular "I Love You China" on the stage of CCTV. Once the program was broadcast, it attracted countless netizens to tears.

　　[Sports] Sun Yang and Xu Jiayu pick gold at the World Championships: be the protagonists together and carry the banner together

　　Sun Yang and Xu Jiayu made breakthroughs at the FINA Swimming World Championships on the 25th, one filling a gap in the individual honor book with the men’s 200m freestyle gold medal, and the other giving Chinese athletes a place on the top podium of the men’s backstroke world championships. The pool at the Danube Swimming Pool saw three people rewrite the world record four times that day, including the British man Peeti in the men’s 50m breaststroke breaking twice in one day.

　　"Discovery" collected a large number of cold spring organisms in the South China Sea

　　On the 25th, the "Discovery" remote-controlled unmanned submersible carried by our country’s new generation of ocean-going comprehensive scientific research vessel "Science" brought back a large number of biological samples from a cold spring area in the South China Sea, including more than 100 biological samples such as submersible armor shrimp, mussels and Alvin shrimp, and took a large number of submarine high-resolution video data.

　　[Ecology] Northwest Ecological Barrier Qilian Mountains: The "Strictest in History" Accountability Storm Brings "Green Revolution"

　　Over the past few days, the Central Office and the State Office have issued a notice on the ecological environment of the Qilian Mountains National Nature Reserve in Gansu Province, which has attracted widespread attention from the society. Up to now, hundreds of people, including three deputy provincial cadres in Gansu Province, have been held accountable for the ecological damage of the Qilian Mountains. This environmental accountability storm, known as the "strictest in history", has also triggered profound reflection among the cadres and people involved.

　　[Science and technology] our country’s space quantum communication technology has made a breakthrough: laying a solid technical foundation for building a quantum constellation

　　Recently, a research team composed of Professor Pan Jianwei of the University of Science and Technology of China and colleagues Peng Chengzhi and Zhang Qiang has successfully realized daytime long-distance (53km) free space quantum key distribution for the first time in the world, and effectively verified the feasibility of future satellite-to-ground and inter-satellite quantum communication networks based on quantum constellations in terms of channel loss and noise level through ground-based experiments. The results were recently published in the international authoritative academic journal Nature Photonics.

　　[Roaming charges] Cancel long-distance roaming charges from September 1

　　Zhang Feng, chief engineer of MIIT, said at the press conference of the State Council Information Office on the 25th that our country will gradually reduce the tariffs for international long-distance calls in more directions. More characteristic broadband products will be launched for industrial parks, "innovation and innovation" enterprises, and will speed up the cancellation of domestic long-distance roaming charges for mobile phones.

　　[Cold Observation] Who made the delivery guy "run all the way"?

　　Worried that the food delivery truck would be towed away, he knelt down and begged for mercy in the street in a hurry; he sent multiple orders in the high temperature, and fainted from heatstroke during the delivery; he was worried that the delivery would be timed out, so he stomped his feet and cried in a hurry… "Kneel", "dizzy" and "cry", reflecting the hardships of the group life of the delivery brother, which made many netizens leave messages "so distressed".

　　[Flood control] The No. 1 flood this year occurred in the Yellow River

　　The reporter learned from the Yellow River Flood Control and Drought Relief Headquarters that at 1:06 on July 27, the Yellow River experienced the No. 1 flood of 2017, with a peak flow rate of 6010 cubic meters per second at the Longmen Hydrological Station located in the middle reaches of the Yellow River.

　　[High temperature] High temperature orange warning: local maximum temperature in 13 provinces exceeds 40 ° C

　　According to the official website of the Central Meteorological Observatory, the Central Meteorological Observatory continued to issue a high temperature orange warning at 6:00 on July 23: During the day on July 23, there were high temperatures above 35 degrees Celsius in the eastern part of the northwest region, Huanghuai, the eastern part of the Sichuan Basin, Jianghan, Jianghuai, Jiangnan, and northern South China.

　　[Medical and Health] Our country has established an "aircraft carrier" for clinical research on major diseases

　　32 national clinical research centers have been built around 11 disease fields such as cardiovascular diseases, malignant tumors, and respiratory diseases. Relying on 30 Tier 1 hospitals with the strongest strength and highest level in the field of disease prevention and control, more than 2,100 medical institutions at all levels in about 260 prefecture-level cities have been combined to form a high-level clinical research platform and collaborative innovation "aircraft carrier formation"…

　　16 shared sleeping cabin business sites in Beijing have stopped operating, and the operators have been interviewed

　　The appearance of "shared sleep capsules" in Zhongguancun, Beijing, has attracted attention. The reporter learned from the Beijing police that the public security organs attach great importance to this. After investigation, it was found that the "shared sleep capsules" are "sleeping space" space capsules developed by a company in Beijing. These space capsules can be used without registering identity information, and are easy to be used by criminals and criminals to hide. The space capsules are closed and have small internal space. After a fire, they cannot be extinguished in time to escape, and there are security and fire hazards.

　　[E-commerce anti-counterfeiting] What signals did Taobao release in the "first case" of winning the sale of counterfeit merchants?

　　According to the information obtained by the Fengxian District People’s Court and Alibaba Group, this is the first case in the country in which an e-commerce platform has prosecuted a fake online store. The industry believes that the judgment of this case will form a deterrent to such illegal acts, play a positive role in mobilizing social co-governance, maintaining fair competition, and improving the consumption environment. It also recommends further improving legislation and strengthening the punitive compensation system to increase the illegal cost of fake sales.

　　Recently, China began to deploy COVID-19 vaccine to strengthen immunization in sequence. So, is sequential vaccination "mixing" different brands of vaccines? In fact, sequential vaccination emphasizes vaccination with different technical routes at intervals. Then why sequential vaccination? Is there a similar deployment abroad?

　　Why sequential inoculation?

　　Sequential inoculation refers to interval inoculation (alternate inoculation) of vaccines with different technical routes. According to Shao Yiming, a member of the expert group of the vaccine research and development special class of the joint prevention and control mechanism in the State Council, China, at the press conference of the joint prevention and control mechanism on the 19th, sequential immunization is often used for viruses with strong variability and difficult to deal with.

　　Wang Huaqing, chief expert of immunization program of China CDC, said that some countries in America, Europe and Southeast Asia have started to implement sequential immunization.

　　The European Medicines Agency and the European Center for Disease Control and Prevention issued a statement in December, 2021, saying that many studies showed that mixed inoculation ("mixed inoculation") of adenovirus vector vaccine and mRNA (messenger RNA) vaccine could "produce a better antibody level" and "produce a better T-cell immune response than vaccines using the same technology". T cells are one of the defenses against diseases in human body.

　　The statement said that "mixed vaccination" can "provide richer vaccination options, especially when a vaccine cannot be vaccinated for some reason, which can reduce the impact on vaccine promotion".

　　Shao Yiming said that there are two main purposes to adopt sequential immunization: one is that different vaccines can complement each other, and the other is that different personal constitutions may have more side effects on a certain type of vaccine, and vaccination with different technical routes can avoid side effects.

　　Temporary guide to "mixed fighting"

　　Based on the existing research data, the World Health Organization issued the interim guidelines for "mixed vaccination" in COVID-19 in December 2021. This guide is based on the recommendations made by the WHO Strategic Advisory Expert Group and is applicable to all COVID-19 vaccines on the WHO emergency use list. The guidelines suggest that if the first dose is a viral vector vaccine, whether the second dose or the booster dose can be vaccinated with mRNA vaccine; or vice versa, Dallas to the auditorium If inactivated vaccine is inoculated at first, viral vector vaccine or mRNA vaccine can be inoculated later.

　　Up to now, the vaccines that have entered the WHO emergency list include: AstraZeneca vaccine in Britain, Johnson & Johnson vaccine, Mardner vaccine and Pfizer vaccine in the United States, Sinopharm vaccine and Kexing vaccine in China, Covaxin vaccine and Covovax vaccine in India, and Novavax vaccine in the United States. Among them, Kexing, Sinopharm and Covaxin are inactivated vaccines, Johnson & Johnson and AstraZeneca are adenovirus vector vaccines, Mardner and Pfizer are mRNA vaccines, and Novavax vaccine and CoVAX are recombinant protein vaccines.

　　According to the provisional guidelines, the existing research mainly involves the influence of "mixed beating" on human immunity. It is still the current standard practice to choose the same vaccine as the first shot when inoculating the second and third shots, but with the deepening of research, WHO will re-evaluate the advantages and risks of "mixed shots". With the release of more research data, it is not excluded to adjust the "mixed play" guide.

　　Many countries approve "mixed fighting"

　　On October 20, 2021, the US Food and Drug Administration revised the authorization for emergency use of vaccines in COVID-19, allowing vaccinators to choose vaccine booster needles with different brands than those previously vaccinated. Peter Marks, director of the Center for Biological Products Evaluation and Research of the US Drug Administration, said that the decision to allow "mixed injections" to strengthen needles aims to meet the needs of the people as much as possible.

　　After studying the test results of Spanish and British mixed vaccination with COVID-19 vaccine, the Canadian National Advisory Committee on Immunization announced new regulations in June 2021, allowing mixed vaccination with COVID-19 vaccine, so as to further accelerate the vaccination progress. The first dose of AstraZeneca vaccine, the second dose can choose the same vaccine, Pfizer or Mardner vaccine.

　　South Korea, Britain and other countries have started clinical trials on sequential vaccination of COVID-19 vaccine. In May 2021, the disease control department of Korea started the clinical trial of sequential vaccination. The first batch of subjects were about 500 people who had been vaccinated with one dose of AstraZeneca vaccine, and the second dose was vaccinated with other COVID-19 vaccines such as Pfizer. The results showed that people who were inoculated with AstraZeneca and Pfizer vaccine in sequence would increase the neutralizing antibody level by 6 times compared with those who were vaccinated with two doses of AstraZeneca vaccine.

　　In February, 2021, Oxford University in the United Kingdom launched a clinical trial of sequential vaccination of COVID-19 vaccine. AstraZeneca vaccine and Pfizer vaccine were mixed in the first phase clinical trial, and Mardner vaccine and Novavax vaccine were used in the second phase trial in April.

　　The results showed that the antibody level of volunteers who were vaccinated with Pfizer vaccine and then AstraZeneca vaccine was about 5 times higher than that of volunteers who were vaccinated with two doses of AstraZeneca vaccine, and the antibody level of volunteers who were vaccinated with AstraZeneca vaccine and then vaccinated with Pfizer vaccine was 9 times higher than that of those who were vaccinated with two doses of AstraZeneca vaccine. Vaccination with AstraZeneca vaccine first and then with Mardner or Novavax vaccine will produce higher antibody level than two doses of AstraZeneca vaccine.

　　According to Xinhua News Agency

　　China news agency, Tokyo, July 26 th, "Let’s let it go about the Rio Olympics and turn it over." Walked down from the men’s 67kg podium, turned his head to one side, waved his left hand and said.

　　On the evening of July 25th, Beijing time, in the men’s weightlifting 67kg class of Tokyo Olympic Games, China’s Chen Lijun won the championship with 145kg in snatch, 187kg in clean and jerk and 332kg in total score, breaking the Olympic records of clean and jerk and total score, and also won the sixth gold medal for the China sports delegation. The picture shows Li Lijun taking off his mask at the award ceremony. China News Service reporter Han Haidan photo

　　This is a night belonging to the imperial army, and the champion needs to digest. That sad night in Rio five years ago also needs to be digested.

　　That sad night was August 8, 2016, the second competition day after the opening of the Rio Olympic Games. After two consecutive snatch failures, the Patent Army withdrew from the men’s weightlifting 62kg gold medal competition.

　　This is an unexpected result. Before the Rio Olympic Games, in the 2015 World Championships in Houston, the Patent Army broke the world record of 62kg and won the championship.

　　The Chenli Army, which played in Rio Olympic Games with a halo, was originally regarded as one of the most stable gold rush points of China weightlifting team. No one expected that the accident would happen.

　　During the warm-up session before the game, Li Lijun suffered from cramps in his legs. In the words of coach Yu Jie, his legs were "as hard as stones". After a simple massage, Chen Lijun felt a little relaxed in his legs, so he tried to snatch 143 kilograms. "But as soon as I grab the barbell, my legs get hard again. I really can’t help it." Chen Lijun said helplessly after the game.

　　Facing the camera, the strong weightlifting man’s eyes were red and he choked and said several "sorry".

　　After retiring from Rio, the Patent Army entered a new round of preparations for the Olympic Games, but it is obviously more difficult to get back what it is about to get than simply winning gold.

　　Returning to the World University Weightlifting Championship, winning the national championship and winning the national games, the Chenli Army slowly regained its mood. "Winning the Tokyo Olympics is proud." One year later, the sorrow of Rio is still in the heart of the patent army.

　　In July 2018, the international weightlifting Federation adjusted the level of weightlifting events, and the 62 kg class was adjusted to the 67 kg class. After the weight gain, the Li Lijun still performed steadily.

　　At the 2018 World Weightlifting Championships, the patent army successfully won the championship by breaking the men’s 67 kg world record with 332 kg. "The next step is to prepare for a new level wholeheartedly. I hope to have a dream in Tokyo!" Every time Chen Lijun is interviewed, it seems that he can’t get away from the topic of Tokyo’s dream.

　　In the men’s 67kg class competition of the World Weightlifting Championships in 2019, the Patent Army made a further breakthrough and won the championship with 337kg. He would not have thought that the 187kg completed in the clean and jerk had laid a great foundation for his dream trip.

　　In 2020, under the epidemic, the Tokyo Olympic Games was forced to be postponed for one year. In October, the Chenli Army suffered a hand injury and needed surgery. "It was a big blow. I never thought I would have surgery in my career." Yan Lijun said.

　　Fortunately, the injured troops did not give up. Five months later, he came back from injury. In the Asian Championships in Tashkent in April, the Chenli Army won the championship with the clean and jerk and the total score. The excellent performance of the "mock exam" of the Tokyo Olympic Games has completely let the troops out of the scruples of injuries.

　　Standing on the stage of dreams, the patent army failed to snatch the second and third consecutive attempts, which had to make people’s thoughts travel back to Rio five years ago. You know, in the snatch of 145 kilograms, this achievement was only tied for fourth place among 10 players, 6 kilograms behind Colombian Mosquera.

　　In the clean and jerk, Mosquera is still strong, with a successful attempt of 180kg, which means that the Chenli Army has to put all its eggs in one basket to lift 187kg in the last two attempts, which is 12kg higher than the previous attempt.

　　Quickly walked onto the stage, grabbed the barbell, and struggled to lift it. Li Lijun steadily lifted 187 kilograms. This is the weight that the Patent Army has never lifted in the competition after the 2019 World Championships. With a breath from Rio to Tokyo, he made a miracle in deus ex from the corner.

　　"Sometimes I think of the bitterness of this road and feel a little like crying, but I will pass if I think about winning the championship later." Chen Lijun, who just stepped off the podium, said excitedly.

　　But obviously, the taste of waiting for five years is not so easy to digest. Half an hour later, when talking about this topic again in the press conference hall, Li Lijun choked and said, "It’s really not easy to walk all the way. I have been trying to win the championship for years. My opponent is very strong in this competition, but I am stronger!"

　　Five years later, another night of tears, the story of the dream of Kouli Army came to a successful conclusion in a ups and downs way, which is also the epitome of the five-year preparations for the Olympic Games. (End)

1905 movie network news As of December 23rd, 2016, the box office of mainland movies exceeded 44.1 billion yuan, and it took 358 days to surpass the total box office of 44.069 billion yuan last year, which is far from the rate of exceeding the box office of 2014 in just over nine months in 2015. This year’s box office growth rate will be lower than 25% for the first time in 13 years. According to the current overall box office trend, the box office growth rate in 2016 is likely to be less than 3%, which is also the slowest year of box office growth in China in the past 17 years.

However, looking back on the film market in 2016, there are still many things worthy of recognition: the box office performance of Xingye reached 3.389 billion yuan, which became the first film in China to break through the 3 billion yuan mark and also set a new record in China film history. This year, single-day, single-week and single-month box office also created the best results in history. In addition, it is worth mentioning that among the films released this year, as many as 84 films have exceeded 100 million yuan at the box office.

Single-chip, single-week, single-month, record-breaking. In February, 6.8 billion box office ranked first in the whole year.

In recent years, China’s film industry has developed rapidly, and the box office has grown from less than 1 billion in 2002 to more than 44 billion today. In just 14 years, the box office has increased 45 times, ranking second in the global film market. In 2010, the growth rate of box office in mainland China reached 64%, and the growth rate of box office in 2009 and 2015 also remained above 40%.

In 2016, after the record-breaking rapid development in the first quarter, the growth rate of box office in China suddenly slowed down, and the box office output declined month by month, which once caused the "panic" of filmmakers. But fortunately, the popular schedule still performed well, especially the summer file saved a lot of decline. In addition, the single-chip "turning the tide" brought the eleventh file and the New Year file. Finally, when there were eight days left in 2016, the box office successfully broke through the 44.1 billion yuan mark, which made it difficult to surpass the total box office in 2015. Although the industry predicted that the annual box office of 60 billion yuan could not be realized at the beginning of the year, this year has also become the first year in 14 years that the growth rate of box office in mainland China has dropped to single digits, but looking back at the whole year, there are still frequent highlights.

Top three movie box office rankings in 2016

This year’s single-film, single-day, single-week and single-month box office have all set new records in film history, which makes people clap their hands. Among them, The Mermaid, directed by Stephen Chow, earned 280 million yuan on the opening day, and reached 310 million yuan on Valentine’s Day on February 14, and surpassed 2.439 billion yuan in 12 days, making it the top box office champion in the mainland film history. "Mermaid" therefore announced a three-month extension, and finally ended with 3.389 billion yuan, becoming the first film in China to rank among the 3 billion clubs.

With The Mermaid and the escort of the Troika released on the same day at the beginning of this year, the February box office with only 29 days was brought to a high of 688,500 yuan, exceeding the highest monthly box office of 5.5 billion yuan set in July last year, successfully refreshing the single-month box office record in China and becoming the first month in the history of mainland film to break 6 billion yuan. February this year is a record year, and from February 8 to February 14,Create a new single-week box office record with a box office output of 3.63 billion yuan.The original box office of 1.78 billion yuan (from July 13 to 19, 2015) doubled. The box office reached a new high that day, with 646 million, 603 million and 526 million box offices on February 8, February 14 and February 9, respectively, ranking among the top three in the single-day box office of the mainland film history.

Five domestic films have grossed more than 1 billion. Who will break the 3.3 billion myth of The Mermaid?

In 2016, the movie "The Mermaid" and "He" won the first, second and third place at the box office in mainland China this year with 3.38 billion yuan, 1.53 billion yuan and 1.47 billion yuan respectively. Mermaid, Monkey King Thrice Defeats the Skeleton Demon on a Journey to the West, operation mekong, storm riders of Macau and five domestic films are among the 1 billion yuan clubs, leading the box office charts of Chinese films this year.

Up to now, a total of 84 Chinese and foreign films released in the mainland have exceeded 100 million at the box office this year, of which 41 Chinese films have exceeded 100 million. However, it just premiered on December 23, and no matter what the word of mouth is, I believe there is no suspense in the box office of the two films exceeding 100 million.

This year, The Mermaid’s box office achievement of 3.3 billion yuan has reached the dust. No matter Xiaogang Feng’s I Can’t Pan Jinlian, or the big IP Tomb Notes, or World of Warcraft and other Hollywood blockbusters, it has failed to shake Stephen Chow’s position. As of 15: 00 on December 23rd, Zhang Yimou’s highly anticipated new work "The Great Wall" had less than 700 million box office, and it was hopeless to surpass The Mermaid.

Then, who will break this record, can only wait until next year, especially on the first day of 2017, nine films will be released together, directed by Tsui Hark, directed by Wang Baoqiang and starring Jackie Chan, and many Hollywood sequel to the movie, etc., will all launch a powerful impact on the single-chip box office record of 3.3 billion.

Since the beginning of this year, the municipal taxation department has taken the opportunity of institutional reform to tailor-made "targeted" service measures for various enterprises, further helping generate, a private economy, to create vitality, to promote the gradual transformation and upgrading of established state-owned enterprises, and to effectively serve enterprises in a new journey of high-quality development. Today and tomorrow, Xiaoyan will take you to know what the tax authorities in our city have done to serve enterprises. Today, let’s take a look at how the municipal tax department serves the development of private enterprises.

Inter-departmental cooperation to support the innovation and development of private enterprises

Private enterprises that support half of China’s economy have contributed more than 70% of technological innovation. In order to make the innovation source of private economy fully flow in, the enjoyment of high-tech tax preferential policies is undoubtedly one of the effective tools.

As the first private enterprise in Shanghai with the qualification to operate a chain Internet cafe, Shanghai Wangyu Information Technology Co., Ltd. revealed to Songjiang District Taxation Bureau the problems encountered by the enterprise in the investigation: the enterprise has a service fee of 38.3443 million yuan for joining the management system, and there are different opinions between the enterprise and the high-tech certification office on whether this income belongs to high-tech products.

The person in charge said: Whether it can be recognized as a high-tech enterprise and enjoy the preferential corporate income tax rate is particularly important for us technological innovation enterprises. If it cannot be identified, it will directly affect the high-tech qualification of our enterprise and the enjoyment of preferential policies.

To this end, the research team of Songjiang District Taxation Bureau immediately reported the problem to the Municipal Taxation Bureau, and the Municipal Bureau cooperated with other departments, actively communicated and negotiated with the Municipal High-tech Certification Office, and decided to hold a special "inquiry meeting" for enterprises to solve the problem. After the research and discussion of experts in the high-tech accreditation industry, the Municipal High-tech Accreditation Office finally recognized the enterprise’s statement and determined that the income can be included in the income of high-tech products. The relevant person in charge of the enterprise said that after successfully solving this problem, enterprises can enjoy a total tax reduction of nearly 5 million yuan in 2016 and 2017.

In addition to policy judgment, how to obtain the qualification certificate of high-tech enterprises faster is also the focus of enterprises’ attention. Many "dual-innovation" enterprises have reflected the "blocking point" problem encountered in the process of high-tech application: the application materials for high-tech certification contain some tax-related information, but the tax-related information is more professional and difficult to fill in. If the preparation is not in place, it is likely to lead to the failure of the "high-tech" application in the current year and delay the time for policy enjoyment.

In view of the problems raised by enterprises, Yangpu District Taxation Bureau and Yangpu District Science and Technology Commission jointly optimized the audit process of high-tech enterprises. The original "serial audit" mode of "science and technology commission first, then tax" was changed to the "parallel audit" mode carried out by two departments simultaneously. After receiving the list of enterprises applying, the district science and technology commission shared it as soon as possible. At the same time, the tax department began to "pre-examine" the tax-related materials, actively reminded and publicized the relevant policies and regulations, and gave enterprises sufficient time to make corrections. Through pre-counseling, the pass rate of enterprises applying for "high-tech" for the first time will be greatly improved, which will add impetus to enterprises’ accelerating the transformation of technological achievements and smoothly entering the fast lane of innovation and development.

Serving "going out" and escorting the overseas development of private enterprises

At present, "going out" is no longer the "patent" of multinational companies and large state-owned enterprises, and many private enterprises, even small and medium-sized enterprises, have begun to take advantage of the wind to go abroad. Recently, the Qingpu District Taxation Bureau conducted a special investigation on this kind of enterprises. Through field visits to a number of high-tech start-up private enterprises such as Huace Navigation and Universal Navigation located in the Beidou Industrial Park of Xihongqiao, it was found that these enterprises have strong technical research and development and market development capabilities, but they often lack sufficient understanding and adaptability to cross-border tax-related policies in the process of "going out to sea".

In order to fill this "short board" and help enterprises avoid potential tax-related risks, researchers have launched a series of classified "targeted" service measures, so that policy guidance can accurately match the pace of enterprise development, including: compiling "Guidelines for Tax Services and Management of Going Out Enterprises", and "peer-to-peer" directional push to 127 enterprises in the area to put a security lock on their cross-border business activities; Specially implement "country-by-country" guidance for small and medium-sized enterprises with high risks due to lack of experience, and invite a group of enterprises with manufacturing projects in Southeast Asian countries to open special exchange meetings; For enterprises that intend to "go out", they should actively communicate with Xihongqiao Development Zone, improve and optimize the service framework systematically through the combination of "regional promotion" and "personalized counseling", and give long-term tax support from the source.

The person in charge of the enterprise revealed that the international environment is complex and changeable, and the unfamiliar tax system and collection and management model are severe challenges. Thanks to the escort of the tax department, it paved the way for the overseas development of the "going out" enterprises in the park.

The relevant person in charge of the Qingpu District Taxation Bureau said: When the comprehensive cross-border tax-related services of the taxation department are combined with the technological advantages of the enterprises’ own products, it not only stimulates the international competitiveness of’ going out’ enterprises, but also sets up a good demonstration effect in the region, so that more enterprises dare to invest in the sea. In just one year, the number of enterprises in the region investing in overseas targets has increased by more than 50, with an additional investment of 2.55 billion yuan.

Pudong New Area is the forerunner of Shanghai’s opening to the outside world and plays an extremely important role in Shanghai’s "going out" strategic planning. Zhongman Oil and Gas Group Co., Ltd. is a private oil service company registered in Pudong. Enterprises seized the opportunity of the "Belt and Road Initiative" and cooperated with Gazprom and Petronas Malaysia to jointly develop drilling business in Middle East countries. By the end of 2017, the amount of foreign investment reached 1.228 billion, and the income from overseas business accounted for more than 80% of the total income.

Faced with such a huge volume, the investigators of Pudong New Area Taxation Bureau tailored the service plan "one-on-one". In order to safeguard the legitimate rights and interests of enterprises and strive for the maximization of tax-related rights and interests, the regional bureau took the initiative to come to the door, introduced the international tax agreements and international common practices to enterprises in detail, advised enterprises to issue the Resident Identity Certificate in time, and helped them successfully complete the credit for the 102 million yuan tax paid in Iraq, effectively serving the "going out" enterprises to achieve stability and prosperity.

After reading today’s content, are you satisfied with the practice of the tax department? Tomorrow, Xiaoyan will show you how the tax department supports the development of large enterprises and traditional state-owned enterprises. See you tomorrow!

(The original title is "How to pay the service fee of 38.34 million Internet cafes? The tax authorities do this ")

In winter,Everyone’s table is bound to get around.Hot pot.Many people want to eat and even can’t live without hot pot.Is eating hot pot healthy?How to eat hot pot scientifically is healthier?

Compared with frying and roasting at high temperature

Hot pot is really healthier.

Compared with frying and barbecue, hot pot is really healthy, because frying and roasting at high temperature will produce harmful substances such as acrylamide, a potential carcinogen. The World Health Organization has listed frying and high-temperature roasting as Class 2A carcinogens, especially foods rich in carbohydrates, which will produce acrylamide when cooked at a high temperature above 120°C, and are clear carcinogens.

In contrast, even the red oil hot pot, the upper floating layer of oil and the lower half of it are all kinds of broth, and the temperature at which the soup boils after heating is about 100℃. In this respect, hot pot is a healthier choice.

Eat a variety of ingredients at one meal

Balanced nutrition hot pot can do it.

According to the dietary guidelines of China residents, it is suggested that everyone should eat at least 12 kinds of food every day. Is it difficult? But a hot pot can simply complete this KPI!

No matter whether it is Chinese food or western food, almost no one can eat a variety of ingredients in one meal like hot pot. There are well-prepared meat, red meat and white meat, leafy vegetables and potatoes, fish and shrimp and internal organs. The variety of food is complete and diverse. From this point of view, the nutritional balance of hot pot is very good!

Does nitrite cause cancer?

There is indeed nitrite in the hot pot. The longer the hot pot is cooked, the higher the nitrite content in the soup. In the hot pot boiled for 90 minutes, nitritesaltContent reached5.2mg/L-15.73mg/L。 However, to achieve nitrite poisoning, it is necessary to ingest 200mg-500mg of nitrite, and reaching this level means drinking about 12.5L of hot pot soup.

Unless a large number of long-term intake of nitrite, lack of antioxidants, or accompanied by gastrointestinal diseases, it may be carcinogenic. Therefore, under normal circumstances, eating hot pot will not cause nitrite poisoning or even cancer.　

How much does hot pot eat to get bowel cancer?

Many people think that one of the reasons why hot pot is unhealthy is spicy. If you eat it often, your stomach can’t stand it, and even think that eating too much spicy hot pot will cause intestinal cancer.

But eating Chili peppers is not necessarily related to the occurrence of intestinal cancer. Therefore, it is unreasonable to think that hot pot is carcinogenic because it is spicy.

There are many reasons that can cause diarrhea after eating, such as stale ingredients, food poisoning caused by food safety problems, allergies to certain foods, and gastrointestinal diseases, etc., but it may be these common and related reasons.

Eat too spicy

Although we just said that pepper is not necessarily related to intestinal cancer, capsaicin in pepper may cause burning and tingling in the gastrointestinal tract of some people, and it will also accelerate the peristalsis of the gastrointestinal tract, leading to diarrhea.

Hotpot+cold drink

Many friends like to eat hot pot with iced coke and iced beer. Some people have nothing to eat and drink, but some people can’t stand it. In fact, it is the cold and hot diet that leads to abnormal contraction of gastrointestinal tract, indigestion and diarrhea.

Eat too long, too much

Eating for a long time will greatly increase the burden on the gastrointestinal tract. The mouth has been eating, and the secretion of digestive juices such as gastric juice, bile and pancreatic juice has not stopped. If this process lasts for several hours, the glands in the digestive tract can’t get normal rest, which may lead to gastrointestinal dysfunction and abdominal pain, diarrhea, etc., and may lead to chronic gastroenteritis, pancreatitis and other diseases.

Eating too hot can easily lead to esophageal cancer.

Too hot food directly into the mouth will not only damage the esophageal mucosa and burn our mouth, but also damage the gastrointestinal mucosa and increase the risk of esophageal cancer.

More oil and more salt.

According to the Dietary Guide for China Residents (2022), adults should not consume more than 5g of salt and 25-30g of cooking oil every day. In fact, China is a big consumer of salt and oil, with an average of 10.5g of salt and 42.1g of oil per day. Moreover, in order to be fragrant and delicious, the bottom of the hot pot is not only rich in oil, but also high in salt. Coupled with the blessing of sesame oil, salt, monosodium glutamate, oyster sauce and other ingredients in the oil dish, after eating a hot pot, the intake of oil and salt casually exceeds the standard.

High purine is easy to cause gout.

① When scalding hot pot, the purine in animal viscera is high.

For example, hairy belly, goose intestines, etc., eating a lot of animal viscera regularly is likely to cause hyperuricemia, so it is even worse for patients who already have hyperuricemia or even gout.

② The soup in the hot pot is high in purine.

Most of the broth in the white pot was originally made of chicken, bones, etc., and the purine content is already relatively high. However, when you put shrimp and meat in the hot pot, the longer you cook, the higher the purine content in the soup will continue to rise.

So how can we eat hot pot healthily?These points suggest Amway to everyone.

(Editor: Lu Ming)

Topic: 2008 US Presidential Election

Mccain and his wife Cindy

　　China Daily Global Online News: In the eyes of people who like him, he is a hero, and his brilliant history records his courage, perseverance and persistence; In the eyes of those who don’t like him, he is a "black-and-white movie" that can’t keep up with the times. At the age of 72, he has to face his own injuries … He is the Republican candidate in the 2008 US presidential election, a senior senator from Arizona, a politician who was born in the door, risked his life on the battlefield, can’t surf the Internet in the contemporary era, but still clings to his dream of the White House.

　　Sensitive and rebellious door nothing.

　　On August 29th, 1936, McCain was born in a US naval base named "Coco Solo" in the Panama Canal area controlled by the United States. Although his parents are both American citizens, being born outside the United States gives McCain a feeling that duckweed has no roots, which gradually develops his restless, competitive and sensitive personality characteristics. Mccain likes reading since he was a child, especially novels and poems about war and love. He looks for spiritual comfort and courage in life in literary works. When he was in middle school, the rebellious McCain was not a good student and was even nicknamed "rogue".

　　Presidents in the United States generally come from two kinds of families, one is that they lack the company of their biological fathers since childhood, and the other is that they are famous and powerful. Democratic presidential candidate Obama belongs to the first category, while McCain belongs to the second category. McCain’s grandfather, John Sidney McCain, is a four-star general in the US Navy. During World War II, he participated in the war against Japan as the commander of the US Pacific Fleet. Mccain’s father was also a four-star admiral. During the Vietnam War, he was the highest commander of the US Navy in the Pacific region.

　　Growing up in such a military family, McCain seems destined to follow the example of his grandfather, father and heroes. Although he admired his grandfather and father, to some extent, he had resented his "inevitable" naval career. After graduating from high school, McCain entered the United States Naval Academy in Annapolis for education. At the school, he was famous for his drinking and chasing the opposite sex, and even almost got fired many times.

　　Vietnam war hero who can’t surf the internet

　　After graduating from the Naval Academy in 1958, McCain joined the United States Naval Air Force and became a naval pilot. Soon he was sent to serve in Vietnam. On October 26, 1967, McCain’s A-4 Skyhawk attack plane was hit by an air defense missile from North Vietnam and crashed. He broke his arms and a leg after ejecting from the plane. Then he was captured by Vietnamese soldiers and tortured all day. But McCain refused to provide any information to the Vietnamese, so he was often beaten unconscious. Unbearable of inhuman torture, McCain tried to commit suicide, but failed.

　　When the Vietnamese learned that McCain’s father was the commander-in-chief of the US Pacific Command Headquarters (CINCPAC), they said they could release him in exchange for McCain writing a confession and admitting that he was a spy, but McCain flatly refused. Only once, McCain couldn’t stand the beating and was forced to sign an anti-American propaganda document written in Vietnamese. Vietnam was later dissatisfied with this document and tried to force him to sign a second statement, but this time McCain refused.

　　In 1973, McCain, who was imprisoned by Vietnamese for five and a half years, was finally released. After returning to China, he became famous and became a hero in people’s minds. Originally, McCain also wanted to follow in the footsteps of his parents and become a four-star general in the navy. However, due to many injuries left during the war and capture, he had to retire from the navy in 1981.

　　A Silver Star Medal, a Bronze Star Medal, a Meritorious Medal, a Purple Heart Medal and a Flying Cross Medal … These brilliant achievements in McCain’s military career have added a lot of color to his presidential campaign. Supporters believe that such a brave and strong hero is more capable of solving the Iraq issue and fighting terrorism.

　　While "history" has become McCain’s advantage, it also inevitably brings him trouble like a double-edged sword. Mccain, who has come from history, is 72 years old. Some people think that he has not kept up with the times, and his ideas and ideas have fallen behind. Even McCain himself admits that he has never sent an e-mail and has just started to "learn to surf the Internet by himself", which does not seem to be competitive in today’s internet age. A Democrat sneered: "It is an anecdote to hear that someone can’t surf the Internet now. My five-year-old niece can play games online … What he did 35 years ago made him a hero, but that doesn’t make him the president of the United States we need today. He is too divorced from the United States today in many ways."

　　"A husband depends on his wife." How do you know the fate?

　　On the way to the White House, McCain had to mention his two marriages, especially his second wife, cindy McCain. Cindy is the daughter of a wealthy beer merchant in Phoenix, Arizona. She inherited her father’s shares and became the chairman of Hansley Beer Distribution Company, with a net worth of more than 100 million dollars. Her strong economic strength not only enables McCain to live a comfortable life with a private jet and a holiday villa, but also her extensive contacts have greatly helped her husband’s political career, so McCain has been described by the outside world as "a husband depends on his wife."

　　Mccain’s first wife, Carol Heep, was a female model from Philadelphia. She had been married once before and had two children. They got married in 1965 and had a daughter. During the five years that McCain was imprisoned during the Vietnam War, Kalou raised three children alone. In 1969, Kalou was seriously injured in a car accident.

　　In 1979, at the age of 42, McCain met 25-year-old Cindy at a party. Although he was still married at that time, McCain fell in love with Cindy at first sight and launched a passionate pursuit. And the marriage between McCain and Carol came to an end in 1980. Shortly after the divorce, McCain married Cindy. Cindy is elegant and low-key, and many Americans have a good impression of her. However, some media disclosed that Cindy had taken painkillers for three years, and this "addict" history may bring trouble to McCain’s campaign.

　　In addition, wealth not only brings "blessing" to the McCain couple, but also becomes the "weapon" of the opponent. In an interview with the media, McCain said that he didn’t know how many properties he and his wife owned. The Obama camp of the Democratic presidential candidate immediately took the opportunity to accuse the "rich man" McCain of not understanding the current economic situation in the United States, and specially produced advertisements to satirize McCain’s high position and ignorance of the sufferings of the people.

　　Mccain and Cindy have two sons and a daughter and adopted a daughter from Bangladesh. Mccain rarely talks about his seven children. It is reported that Jimmy McCain, McCain’s 19-year-old son, served in the battlefield in Iraq and returned to China at the beginning of this year. It is said that McCain personally visited Iraq last year and spent Thanksgiving with a group of American troops stationed in Iraq. In fact, he was visiting his son and his troops.

　　Challenge unlimited oath to enter the White House.

　　After entering politics, McCain walked smoothly with the help of his wife Cindy. In 1982, he was elected to the House of Representatives of Arizona’s first constituency, and later he was elected to the Senate in 1986 and has been re-elected to this day. In 1997, Time magazine listed McCain as one of the "25 most influential people in America".

　　As a politician, McCain was not satisfied with "standing still". His longing for the White House lasted for 10 years. In the 2000 presidential election, John McCain ran for the Republican nomination, but was defeated by george walker bush. In the 2004 US presidential election, McCain always stood on the side of Bush’s camp. After the mid-term election in 2006, McCain formed a research group to investigate the possibility of running for president in 2008, and announced his participation in the 2008 US presidential election on February 28th, 2007. With high political popularity and tough style, McCain finally won the Republican presidential nomination in early March this year.

　　If he wins the election in 2008, 72-year-old McCain will be the oldest person to enter the White House for the first time in American history. But at the same time, public opinion is generally worried about McCain’s age and health. Mccain suffered from melanoma and left many injuries when he was captured in Vietnam. Therefore, some opponents pointed out that no matter how tough "military style" McCain showed, he was helpless "Lian Po was old", and it was hard to believe that his age and physical condition could shoulder the heavy responsibility of governing the country. (Sardonar Lee)

Editor: Zhang Renhe

　　China news agency, Paris, December 15 (Reporter Yang Li) France resumed the curfew on the 15th local time to cope with the COVID-19 epidemic. French Prime Minister Castay said on the same day that it was impossible to determine when the restaurant would reopen because the epidemic was still going on.

Data Map: The streets of Paris, France. China News Service reporter Yang Li photo

　　According to the French official arrangement, people will no longer need a travel certificate to travel during the day from the 15th. However, due to the resumption of the curfew on the 15 th, people still need travel certificates when they go out during the curfew. The official said that the inspection during the curfew period will be strengthened, and those who violate the curfew or do not bring travel certificates will face punishment.

　　Since France was unable to reach the goal of "unblocking" the number of newly confirmed cases in a single day to less than 5,000 on the 15th, the government made substantial adjustments to the "unblocking" scheme. After France resumed the curfew on the 15th, the curfew time will start at 8 pm and end at 6 am the next day. There will be no curfew on Christmas Day, but it will still be imposed on New Year’s Eve on December 31st. France imposed a curfew in October, when the curfew period was from 9 pm to 6 am the next day.

　　French Prime Minister Castay said on the 15th that if the epidemic situation did not improve after the Christmas and New Year holidays, he could not guarantee that restaurants and cafes would reopen on January 20th next year. He said that it is uncertain when the restaurant will reopen.

　　Restaurants and cafes have been closed for one and a half months since France implemented the second national "city closure" on October 30. Castay said that the closure of the relevant sites was a "heartbreaking" decision, but it was necessary to control the epidemic. He said that many European countries have made similar decisions.

　　Castay pointed out that when the restaurant will reopen will depend on "all of us" and how people spend the Christmas and New Year holidays safely. He warned that holiday celebrations may help accelerate the spread of the virus, so people must be jointly responsible for their actions.

　　In addition, the French government has decided that museums, theaters, cinemas and other cultural places cannot be reopened on the 15th, and this opening time may be postponed until January next year. Castay said that he will evaluate whether cultural venues can be reopened with the Minister of Culture and others on January 7 next year.

　　According to the epidemic data released by the French Ministry of Health on the evening of 15th, there were 11,532 new confirmed cases in France on the 15th, and the cumulative confirmed cases were close to 2.4 million, accounting for 2,391,447 cases. There are 59,072 deaths in COVID-19, with 790 new deaths.

　　Recently, National Medical Products Administration reported that Changchun Changsheng Biotechnology Co., Ltd. (hereinafter referred to as "Changchun Changsheng") illegally produced rabies vaccine, and there were some behaviors such as record fraud. The death rate of rabies is almost 100%, and the falsification of vaccine production records has aroused widespread concern in society.

Notice of National Medical Products Administration on the illegal production of freeze-dried rabies vaccine for human use by Changchun Changsheng Biotechnology Co., Ltd. (No.60, 2018)

Published on July 15, 2018

According to the clues, National Medical Products Administration organized a flight inspection of Changchun Changsheng Biotechnology Co., Ltd., and found that there were serious violations of the good manufacturing practice in the production of freeze-dried rabies vaccine for human use.

National Medical Products Administration has asked Jilin Food and Drug Administration to take back its GMP Certificate (certificate number: JL20180024), ordered it to stop the production of rabies vaccine, instructed the enterprise to strictly implement the main responsibility, comprehensively investigate potential risks, and take the initiative to take control measures to ensure the safety of public medication. The investigation team of Jilin Food and Drug Administration has been stationed in the enterprise to investigate the relevant violations of laws and regulations. National Medical Products Administration sent a special inspection team to Jilin to supervise the investigation and disposal.

All batches of products involved in this flight inspection have not yet left the factory and gone on sale, and all products have been effectively controlled.

National Medical Products Administration always puts the safety of people’s medication in the first place, resolutely implements the "four strictest" requirements of the Supreme Leader General Secretary, and will not tolerate the problems found in violation of laws and regulations, and resolutely investigate and deal with them severely according to the law. Anyone suspected of constituting a crime will be transferred to the public security organs for severe punishment.

This is for your information.

the State Drug Administration (SDA)

July 15, 2018

On July 17, Changchun Changsheng issued a statement saying that it had stopped the production of rabies vaccine as required and "deeply apologized". In this regard, many people said that such a big thing should not just be "apologized" but should be "punished".So, should Changchun Changsheng be "punished"? In this regard, the reporter interviewed relevant experts and scholars.

Is the vaccine with false production records a fake drug?

The reporter learned that Article 101 of the Drug Administration Law clearly stipulates that vaccines belong to drugs: drugs refer to substances that are used to prevent, treat and diagnose human diseases, purposefully regulate human physiological functions, and specify indications or functional indications, usage and dosage, including Chinese herbal medicines, Chinese herbal pieces, Chinese patent medicines, chemical raw materials and their preparations, antibiotics, biochemical drugs, radioactive drugs, serum, vaccines, blood products and diagnostic drugs. Ruan Qilin, a professor at China University of Political Science and Law and vice president of china law society Criminal Law Research Association, pointed out that National Medical Products Administration imposed administrative punishment on the rabies vaccine produced by Changchun Changsheng for violating the good manufacturing practice, which also confirmed that China recognized rabies vaccine as a drug.

So, is the vaccine that produces false records a fake drug? Article 48 of the Drug Administration Law stipulates that drugs containing ingredients that are inconsistent with those stipulated in the national drug standards, and those that pass off non-drugs as drugs or pass off other drugs as such drugs are counterfeit drugs. Ruan Qilin said that the "ingredient mismatch" referred to by counterfeit drugs refers to the inconsistency of ingredient types, rather than the substandard content of ingredients.

The reporter learned that the production record is the basic label and file of the product, which not only records the production process of the enterprise, but also records the basic information of the product such as raw materials, preparation, composition, performance, production date and sales destination. "The specific situation of production record fraud is related to the identification of whether the rabies vaccine involved is a counterfeit drug." Liu Junhai, a professor at Renmin University of China and vice president of China Consumers Association, said that the details of Changchun Changsheng’s fraudulent vaccine production records need further investigation.

"If the rabies vaccine involved in the case is fraudulent in the type of active ingredients, it should be considered as a counterfeit drug."Ruan Qilin said that if it is suspected of changing the expiration date or production batch number and reducing the content of active ingredients, it should be identified as inferior drugs according to Article 49 of the Drug Administration Law.

Can you be exempted from legal responsibility without causing adverse reactions?

Although National Medical Products Administration has imposed administrative punishment on Changchun Changsheng for falsifying production records, the company’s claim that all rabies vaccines of the company "have not had any adverse reactions due to product quality problems" cannot rule out the possibility that the company may constitute a criminal offence.

Liu Junhai introduced that the production and sale of counterfeit drugs is enough to seriously endanger human health, which constitutes the crime of producing and selling counterfeit drugs, which is a dangerous crime in criminal form. Article 3 of the Interpretation of the Supreme People’s Court and the Supreme People’s Procuratorate on Several Issues Concerning the Specific Application of Laws in Handling Criminal Cases of Producing and Selling Fake and Inferior Commodities (hereinafter referred to as the Interpretation) stipulates that if the counterfeit drugs produced and sold are identified by the drug inspection institutions set up or determined by the drug supervision and administration departments at or above the provincial level, they shall be deemed as "enough to seriously endanger human health" as stipulated in Article 141 of the Criminal Law: containing excessive toxic and harmful substances; Does not contain the marked effective ingredients, which may delay the diagnosis and treatment; The indicated indications or functional indications are beyond the prescribed scope, which may cause delay in diagnosis and treatment; Lacking the marked effective ingredients necessary for first aid.

"Once the vaccine involved does not contain the active ingredients indicated in the production records, the potential vaccinators will be in danger." Qi Qilin said.

The reporter learned that the rabies vaccine involved in Changchun Changsheng was not listed for sale. If the production record is only fraudulent in composition content or the expiration date is changed, then the rabies vaccine belongs to "inferior medicine" according to relevant regulations.

Ruan Qilin told reporters that the crime of producing and selling inferior drugs in criminal law belongs to the real crime, and it can only constitute a crime if it has caused serious harm to human health. "If the production and sale of inferior drugs do not cause serious harm to human health, it does not constitute the crime of producing and selling inferior drugs. However, if the sales amount is more than 50,000 yuan, it should constitute the crime of producing and selling fake and inferior products according to the provisions of Article 149 of the Criminal Law." Ruan Qilin said that although Changchun Changsheng has no sales behavior, according to Article 2 of the Interpretation, if the fake and inferior products have not been sold and the value of the goods reaches more than three times the sales amount stipulated in the Criminal Law, they will be convicted and punished for the crime of producing and selling fake and inferior products (attempted). That is to say, in this case, as long as the value of the rabies vaccine involved reaches 150,000 yuan, it can be concluded that Changchun Changsheng constitutes the crime of producing fake and inferior products.

If Changchun Changsheng’s production record of rabies vaccine involved in the case is not related to the fraud of items listed in Articles 48 and 49 of the Drug Administration Law, but other general production records, Ruan Qilin said that in this case, Changchun Changsheng will not constitute a crime, but the production record fraud violates the good manufacturing practice, and administrative responsibility is inevitable.

How to standardize the honest production of pharmaceutical companies?

It is understood that Changchun Changsheng has not been named for the first time. On November 3, 2017, the former State Food and Drug Administration detected that the titer index of DTP vaccine with batch number 201605014-01 produced by Changchun Changsheng did not meet the standard.

"Why do pharmaceutical companies refuse to change their education? The key is that the illegal cost of pharmaceutical companies is too low, and they are fined, changed their drug names and continued to operate. " Liu Junhai said that in order to achieve the effect of dealing with one piece of education, we must grasp the typical cases and deal with them strictly according to law. Once Changchun Changsheng constitutes a criminal offence, it should not only bear the corresponding criminal responsibility, but also strictly implement the industry ban system.

The reporter learned that Article 75 of the Drug Administration Law clearly stipulates that the directly responsible person in charge and other directly responsible personnel of enterprises or other units engaged in the production and sale of counterfeit drugs and the production and sale of inferior drugs shall not engage in drug production and business activities within ten years. "In addition to strictly implementing the supervision of pharmaceutical companies, relevant government departments should actively guide pharmaceutical companies to establish the concept of safety first and honest management, and enhance the credibility and core competitiveness of vaccine manufacturers." Liu Junhai said.

There are still four questions to be solved behind the immortal creatures.

Ask

Why did it take nearly 9 months to announce the punishment decision?

On July 15th, National Medical Products Administration notified Changchun Changsheng Rabies Vaccine, a subsidiary of Changsheng Bio, of the problem of falsification of production records, and the lid of the problematic vaccine was uncovered due to an insider’s report. Jilin Food and Drug Administration has withdrawn its GMP Certificate and stopped the production of rabies vaccine. The investigation is still going on. As of the last trading day, Changsheng Bio shares have been down for five consecutive days. Meanwhile, another cover was opened. On July 19, Changsheng Bio issued an announcement and received a penalty decision on the old case of DTP vaccine.

On July 20th, Jilin Food and Drug Administration made this decision public in official website, and the date of signature was July 18th.

It has been nearly nine months since this decision was made. It was only three days after the incident of rabies vaccine.

What is the consideration for this time arrangement? Voice of China reporter called several people in charge of Jilin Food and Drug Administration several times last night, but no one answered or hung up the reporter’s call.

Second question

Where is the problem vaccine?

The penalty decision stated that 186 remaining vaccines in stock were confiscated. However, beyond the inventory, 252,600 problematic vaccines have been sold to Shandong Provincial Center for Disease Control and Prevention. Where are these vaccines? Among the public reports, a report published in the Beijing News on November 5 last year mentioned — — The report quoted the person in charge of the marketing department of Shandong Food and Drug Administration as saying: 1. Relevant departments are carrying out the recall work; 2. The problem drugs have all been sealed. 3. There is no problem with the safety of this batch of drugs, but the titer is not up to standard. At present, no cases of problems with the vaccination of this batch of vaccines have been found.

　

Regarding the statement of safety, experts from China Center for Disease Control and Prevention confirmed that it may affect the immune protection effect, but the risk of vaccination safety has not increased.

But how many vaccines have entered the market? Is it all sealed up, or is it true that some children have been injected with the problem vaccine, and how many? Are there any children who are sick and have their health damaged because of the problem vaccine? How do parents judge whether their children are vaccinated with a problem vaccine and whether there are any relief channels?

Voice of China reporter tried to ask the relevant person in charge of Shandong Food and Drug Administration last night, but did not get a reply. On the other hand, the State Administration of Markets said that it would consider responding to relevant issues on Monday.

Three questions

Are immortals hiding something?

According to the Measures for the Administration of Information Disclosure of Listed Companies, when a company is suspected of violating laws and regulations and is investigated by the competent authorities, and investors have not yet learned about it, the listed company shall immediately disclose the cause, current status and possible impact of the incident. However, it was not until three days ago that Changsheng Bio broke the silence, disclosed the penalties and admitted that the DTP workshop had stopped production.

According to another report in shanghai securities news, in the 2015 annual report of Changsheng Bio, the number of DTP batches issued by the company was about 5.62 million, ranking first among the six vaccine products sold by the company. In the annual reports of the company in 2016 and 2017, it was still stated that the products sold by Changchun Changsheng included DTP vaccine, but the batch number of vaccines was not disclosed. Another change is that DTP has also disappeared in the company’s product picture list for sale in the past two years.

When did the company stop the production of DTP vaccine? The announcement didn’t say.

Last night, no one answered the external calls of Changsheng Bio.

On July 20, Shenzhen Stock Exchange issued a letter of concern, requesting Changsheng Bio to make supplementary explanations on the proportion of products in the company’s revenue, the specific impact on the company and the countermeasures to be taken by the company. In addition, the company is required to explain whether there is any untimely information disclosure and other matters such as the company’s production and operation.

At the regular press conference of the CSRC on the same day, Gao Li, spokesperson of the CSRC, also talked about the information disclosure of listed companies. She said that with the continuous strengthening of supervision and law enforcement, the disclosure quality of financial information of listed companies has been greatly improved in recent years, but the disclosure quality of other major events still needs to be improved. All major events that may have a greater impact on the stock trading price of listed companies should be disclosed in time according to law, fully explaining the cause, current status and possible impact of the event. In the next step, the CSRC will do a good job in related work and severely crack down on various types of illegal information disclosure.

Gao Li: "The information disclosure obligations stipulated in the Securities Law and the Measures for the Administration of Information Disclosure of Listed Companies are diverse and rich in content. Any major event that may have a great impact on the stock trading price of listed companies should be disclosed in time according to law, fully explaining the cause, current status and possible impact of the event."

Four questions

Is the punishment of Jilin Food and Drug Administration too light?

The penalty decision shows that for the DTP vaccine involved, a total of 858,800 yuan of illegal income was confiscated, and a fine of 2.584 million yuan was imposed for three times the value of illegally produced drugs.

A total of 250,000 problematic vaccines were fined 3,442,900 yuan, and there were many doubts.

However, the punishment decision also clarifies the punishment basis — — According to the Drug Administration Law, those who produce and sell inferior drugs shall have their illegally produced and sold drugs and illegal income confiscated, and shall be fined for more than one time and less than three times the value of illegally produced and sold drugs; Inferior drugs are mainly used by pregnant women, infants and children, and will be severely punished within the scope of punishment.

On the other hand, the Drug Administration Law also stipulates that if the circumstances of producing and selling inferior drugs are serious, it shall be ordered to stop production, suspend business for rectification or revoke the drug approval documents and relevant licenses; If a crime is constituted, criminal responsibility shall be investigated according to law.

Many legal professionals told reporters that within the existing legal framework, triple punishment is indeed a "heavier punishment"; As for whether the circumstances are "serious", it is difficult to determine that there is no evidence to prove that the DTP vaccine involved has had a great impact. However, they also said that China’s current handling of similar violations of laws and regulations is light and the warning is not enough.

A senior lawyer suggested that similar acts should be capped with ten times punishment, but he also admitted that the current Drug Administration Law was revised only 15 years ago, and it is unlikely to be revised again in a short time.

　　In order to pay tribute to the 40 years of reform and opening-up, TV dramas with realistic themes have occupied more than half of the screen. Recently, the Entrepreneurial Times, Many Years You Are Late and Little Women under Zhengyangmen, which are intensively broadcasted by many satellite TV stations, all focus on entrepreneurs in different years and fields. On November 5th, another entrepreneurial drama "When the Wind Comes Again" landed on Hunan Satellite TV. This theme work, starring Lu Yi and Yolanda, focuses on economic development and shows the process of economic development in China since the reform and opening up. In addition, tribute dramas such as Our Forty Years, You and My Allure Time will be broadcast one after another in recent days, and a number of highly anticipated entrepreneurial dramas such as Big Rivers will also meet the audience soon. The time line of these TV dramas spans 40 years after the reform and opening up, which also shows that investors and producers of TV dramas are increasingly turning their attention to the ever-changing realistic themes, among which various workplace dramas and industry dramas are the most important. These works let the audience reread the changes of the times of reform and opening up with the plot.

　　Entrepreneurial stories are even more "earthy"

　　At the time of 40 years of reform and opening up, many satellite TV stations have focused their broadcasts on entrepreneurial dramas or industry dramas this year. Prior to this, Ruyi’s Royal Love in the Palace, which was shot with a huge sum of money, was cold after broadcast, which seemed to indicate that the momentum of Gongdou theme was getting weaker and weaker. Previously, the hit Story of Yanxi Palace appeared to be a strong continuation of Gong Dou’s works, but one of the core reasons for its popularity was that the audience needed to watch "cool" dramas. The protagonist’s process of overcoming difficulties was like playing monsters, which made many professionals relieve their pressure and enjoy themselves, which actually indicated the potential market space of workplace dramas and industry dramas.

　　Focusing on the current screen, Entrepreneurial Times, Many Years You’re Late and Little Women under Zhengyangmen are broadcast at the same time, allowing the audience to look back on the entrepreneurial stories after the reform and opening up and show their expectations for the development of emerging industries. Several entrepreneurial dramas broadcast earlier this year have also broadened the field of industry dramas. Compared with the mother-in-law, palace fighting and fantasy themes that were full of screens in the previous two years, this year’s TV screen seems to be connected with the local atmosphere.

　　In November, the works of the 40th anniversary of the reform and opening-up will also enter the climax of broadcasting. "When the Wind Comes Again" starring Lu Yi, Yolanda, zhuyuchen and others landed on Hunan Satellite TV on November 5. Based on the experiences of Fang Bangyan, He Youlin, and Kang Ning who switched jobs and entered the enterprise and government, the drama runs through the historical nodes such as southern talks, establishing the goal of socialist market economy, foreign trade system reform, Asian financial crisis, WTO accession, and Belt and Road construction. It is a work that describes the achievements of reform and opening up in the past 40 years from an economic perspective and restores the reform and opening up.

　　Zhao Liying and Kim starred in "You and My Allure Time", which will be premiered on Oriental TV and Zhejiang TV on November 11th. The play is adapted from Ding Mo’s novel of the same name, and tells the story that Lin Shao, an urban white-collar worker, met Li Zhicheng, who was ordered to become the president because of the business difficulties of his family business. They supported each other and grew together, bringing the business back to life. With the dream of rejuvenating the enterprise and patriotism, young private entrepreneurs such as Li Zhicheng and Lin Qian refused the acquisition of overseas enterprises and devoted themselves to product upgrading and corporate image management. In the end, the two men made the enterprise go to the world step by step and gained love.

　　Our Forty Years, which was also broadcast on November 11th, was adapted from the novel Television. This drama takes the television industry as the breakthrough point and tells the story that Feng Du, a teenager who grew up in an old Beijing hutong in the late 1970s, became attached to the television for the first time and was deeply shocked by the world on the screen. From then on, he took television as his career and gradually became a successful TV man.

　　The theme of entrepreneurship is difficult to be "professional"

　　Although the broadcast of entrepreneurial works has gradually reached a climax, judging from the word-of-mouth situation of the broadcast entrepreneurial dramas, the online rating of Little Women under Zhengyangmen has remained above 8 points, while the ratings of other works are all around 3 to 6 points. Although the audience praised the glitter of some works, for example, after the broadcast of You are Many Years Late, everyone saw that every role in the drama had shortcomings, and they were growing with the broadcast of the series, and they affirmed it.

　　However, many viewers still don’t agree with such works labeled as professional dramas, entrepreneurial dramas or industry dramas. One of the key reasons is that most of the works are dressed as industry dramas, but in fact, they interpret the drama of emotional dramas or chronological dramas, and there is no "industry" reality: "Entrepreneurial Times" is the work that uses the most pen and ink to describe mobile Internet entrepreneurship, but the suspended plot, the deliberately pursued conflict effect, and the abrupt expression and plot all make it difficult for the professionals as the audience to resonate; The little woman under Zhengyangmen, with a high score, talked about the reform and opening up from the public-private partnership in 1955, but it mainly reflected the ups and downs of private enterprises in the long river of history. The elements of workplace and entrepreneurship are not the main theme, but more like an "emotional drama of the times". In addition, several works with industry dramas as their selling points have not won a good reputation from the audience, and the workplace elements are either too thin or seriously out of touch with reality, which is the main reason why industry works have been criticized. After reading it, some viewers said that such works show the "parallel world" of the workplace built by directors or screenwriters according to their imagination without experiencing life.

　　Clever playwrights in the workplace are better at promoting the development of the plot with internal contradictions in the industry. What the audience sees is the survival law and struggle process in the workplace, as well as the entanglement between good and evil in human nature caused by these. In the history of domestic dramas, there have also been workplace industry dramas with win-win reputation and ratings. In the 1980s, Miss Public Relations, Plainclothes Policeman and the popular hit Mind in previous years interpreted the vivid but little-known lives of all kinds of professionals.

　　A successful entrepreneurial drama can highly restore the professional characteristics of a certain field and set up people with industry characteristics. The first thing to do is to be professional, and professionalism means that the main creator is close to the real life and work state of the people in the workplace, so that the audience can feel the joys and sorrows of the characters in the drama. (Reporter Qiu Wei)